If you have logged donations in your account you can segment down on those donations. To segment on donations go to Audience > Search.
Then chose Activity > Donations on the criteria tab. You then have the ability to drill down by Donation Drive Name, Datetime, Organization, minimum and maximum amount, Recurring Donation, Bundler ID, Collection Method, Payment Method, Source Code, External ID, Donation Subscription ID, Donation Program, Donation Program Code, Donation Package, Donation Package Code, Donation Fund, Donation Fund Code, Donation Account Code, or Donation Initiative Code.
After you've made your donation criteria selections, click "Save Selections" and proceed with editing your segment.